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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
01/12/2023 |
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Data da última atualização: |
15/02/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
CARRARA, E. R.; LOPES, P. S.; VERONEZE, R.; PEREIRA, R. J.; ZADRA, L. E. F.; PEIXOTO, M. G. C. D. |
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Afiliação: |
UNIVERSIDADE FEDERAL DE VIÇOSA; UNIVERSIDADE FEDERAL DE VIÇOSA; UNIVERSIDADE FEDERAL DE VIÇOSA; UNIVERSIDADE FEDERAL DE RONDONÓPOLIS; CENTRO BRASILEIRO DE MELHORAMENTO GENÉTICO DO GUZERÁ; MARIA GABRIELA CAMPOLINA DINIZ PEIX, CNPGL. |
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Título: |
Assessment of runs of homozygosity, heterozygosity-rich regions and genomic inbreeding estimates in a subpopulation of Guzerá (Bos indicus) dual-purpose cattle. |
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Ano de publicação: |
2024 |
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Fonte/Imprenta: |
Journal of Animal Breeding and Genetics, v. 141, n. 2, p. 207-219, 2024. |
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DOI: |
https://doi.org/10.1111/jbg.12836 |
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Idioma: |
Inglês |
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Conteúdo: |
For decades, inbreeding in cattle has been evaluated using pedigree information. Nowadays, inbreeding coefficients can be obtained using genomic information such as runs of homozygosity (ROH). The aims of this study were to quantify ROH and heterozygosity-rich regions (HRR) in a subpopulation of Guzerá dual-purpose cattle, to examine ROH and HRR islands, and to compare inbreeding coefficients obtained by ROH with alternative genomic inbreeding coefficients. A subpopulation of 1733 Guzerá animals genotyped for 50k SNPs was used to obtain the ROH and HRR segments. Inbreeding coefficients by ROH (FROH), by genomic relationship matrix based on VanRaden's method 1 using reference allele frequency in the population (FGRM), by genomic relationship matrix based on VanRaden's method 1 using allele frequency fixed in 0.5 (FGRM_0.5), and by the proportion of homozygous loci (FHOM) were calculated. A total of 15,660 ROH were identified, and the chromosome with the highest number of ROH was BTA6. A total of 4843 HRRs were identified, and the chromosome with the highest number of HRRs was BTA23. No ROH and HRR islands were identified according to established criteria, but the regions closest to the definition of an island were examined from 64 to 67 Mb of BTA6, from 36 to 37 Mb of BTA2 and from 0.50 to 1.25 Mb of BTA23. The genes identified in ROH islands have previously been associated with dairy and beef traits, while genes identified on HRR islands have previously been associated with reproductive traits and disease resistance. FROH was equal to 0.095 ± 0.084, and its Spearman correlation with FGRM was low (0.44) and moderate-high with FHOM (0.79) and with FGRM_0.5 (0.80). The inbreeding coefficients determined by ROH were higher than other cattle breeds' and higher than pedigree-based inbreeding in the Guzerá breed obtained in previous studies. It is recommended that future studies investigate the effects of inbreeding determined by ROH on the traits under selection in the subpopulation studied. MenosFor decades, inbreeding in cattle has been evaluated using pedigree information. Nowadays, inbreeding coefficients can be obtained using genomic information such as runs of homozygosity (ROH). The aims of this study were to quantify ROH and heterozygosity-rich regions (HRR) in a subpopulation of Guzerá dual-purpose cattle, to examine ROH and HRR islands, and to compare inbreeding coefficients obtained by ROH with alternative genomic inbreeding coefficients. A subpopulation of 1733 Guzerá animals genotyped for 50k SNPs was used to obtain the ROH and HRR segments. Inbreeding coefficients by ROH (FROH), by genomic relationship matrix based on VanRaden's method 1 using reference allele frequency in the population (FGRM), by genomic relationship matrix based on VanRaden's method 1 using allele frequency fixed in 0.5 (FGRM_0.5), and by the proportion of homozygous loci (FHOM) were calculated. A total of 15,660 ROH were identified, and the chromosome with the highest number of ROH was BTA6. A total of 4843 HRRs were identified, and the chromosome with the highest number of HRRs was BTA23. No ROH and HRR islands were identified according to established criteria, but the regions closest to the definition of an island were examined from 64 to 67 Mb of BTA6, from 36 to 37 Mb of BTA2 and from 0.50 to 1.25 Mb of BTA23. The genes identified in ROH islands have previously been associated with dairy and beef traits, while genes identified on HRR islands have previously been associated with ... Mostrar Tudo |
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Palavras-Chave: |
Autozigosidade; Autozygosity. |
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Thesagro: |
Bovino; Gado de Corte; Gado Guzerá; Gado Leiteiro; Marcador Genético. |
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Thesaurus Nal: |
Beef cattle; Dairy cattle; Genetic markers; Zebu. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 03045naa a2200325 a 4500
001 2159024
005 2024-02-15
008 2024 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1111/jbg.12836$2DOI
100 1 $aCARRARA, E. R.
245 $aAssessment of runs of homozygosity, heterozygosity-rich regions and genomic inbreeding estimates in a subpopulation of Guzerá (Bos indicus) dual-purpose cattle.$h[electronic resource]
260 $c2024
520 $aFor decades, inbreeding in cattle has been evaluated using pedigree information. Nowadays, inbreeding coefficients can be obtained using genomic information such as runs of homozygosity (ROH). The aims of this study were to quantify ROH and heterozygosity-rich regions (HRR) in a subpopulation of Guzerá dual-purpose cattle, to examine ROH and HRR islands, and to compare inbreeding coefficients obtained by ROH with alternative genomic inbreeding coefficients. A subpopulation of 1733 Guzerá animals genotyped for 50k SNPs was used to obtain the ROH and HRR segments. Inbreeding coefficients by ROH (FROH), by genomic relationship matrix based on VanRaden's method 1 using reference allele frequency in the population (FGRM), by genomic relationship matrix based on VanRaden's method 1 using allele frequency fixed in 0.5 (FGRM_0.5), and by the proportion of homozygous loci (FHOM) were calculated. A total of 15,660 ROH were identified, and the chromosome with the highest number of ROH was BTA6. A total of 4843 HRRs were identified, and the chromosome with the highest number of HRRs was BTA23. No ROH and HRR islands were identified according to established criteria, but the regions closest to the definition of an island were examined from 64 to 67 Mb of BTA6, from 36 to 37 Mb of BTA2 and from 0.50 to 1.25 Mb of BTA23. The genes identified in ROH islands have previously been associated with dairy and beef traits, while genes identified on HRR islands have previously been associated with reproductive traits and disease resistance. FROH was equal to 0.095 ± 0.084, and its Spearman correlation with FGRM was low (0.44) and moderate-high with FHOM (0.79) and with FGRM_0.5 (0.80). The inbreeding coefficients determined by ROH were higher than other cattle breeds' and higher than pedigree-based inbreeding in the Guzerá breed obtained in previous studies. It is recommended that future studies investigate the effects of inbreeding determined by ROH on the traits under selection in the subpopulation studied.
650 $aBeef cattle
650 $aDairy cattle
650 $aGenetic markers
650 $aZebu
650 $aBovino
650 $aGado de Corte
650 $aGado Guzerá
650 $aGado Leiteiro
650 $aMarcador Genético
653 $aAutozigosidade
653 $aAutozygosity
700 1 $aLOPES, P. S.
700 1 $aVERONEZE, R.
700 1 $aPEREIRA, R. J.
700 1 $aZADRA, L. E. F.
700 1 $aPEIXOTO, M. G. C. D.
773 $tJournal of Animal Breeding and Genetics$gv. 141, n. 2, p. 207-219, 2024.
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
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| Registros recuperados : 33 | |
| 5. |  | ARRUDA, R. J.; PEREZ, D. V.; ALCANTARA, S. de; MENEGUELLI, N. do A. Comparação de métodos de determinação de carbono em alguns tipos de solos brasileiros. In: CONGRESSO BRASILEIRO DE CIÊNCIA DO SOLO, 27., 1999, Brasília, DF. Resumos [...]. Planaltina, DF: Embrapa Cerrados, 1999. 1 CD-ROM.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Solos. |
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| 9. | | PEREZ, D. V.; ALCANTARA, S. de; RONA, G. B.; POLIDORO, J. C.; BETTIOL, W. Chemical changes in an Oxisol cultivated with maize (Zea mays, L.) after six years disposal of sewage sludge. International Journal Environmental Engineering, v. 4, n. 3-4, p. 352 -371, 2012. 20 p.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 4 |
| Biblioteca(s): Embrapa Meio Ambiente; Embrapa Solos. |
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| 11. | | PÉREZ, D. V.; ALCÂNTARA, S. de; RONA, G. B.; BETTIOL, W.; MORICONI, W. Efeito residual da aplicação de biossólido. In: REUNIÃO BRASILEIRA DE FERTILIDADE DO SOLO E NUTRIÇÃO DE PLANTAS, 28., 2008; REUNIÃO BRASILEIRA SOBRE MICORRIZAS, 12., 2008; SIMPÓSIO BRASILEIRO DE MICROBIOLOGIA DO SOLO, 10., 2008; REUNIÃO BRASILEIRA DE BIOLOGIA DO SOLO, 7., 2008, Londrina. FertBio 2008: desafios para o uso do solo com eficiência e qualidade ambiental: anais. Londrina: Embrapa Soja: SBCS: IAPAR: UEL, 2008. 4 p. Organizado por Adilson de Oliveira Junior, Regina Maria Villas Bôas de Campos
Leite, César de Castro, Fábio Álvares de Oliveira, Odilon Ferreira Saraiva.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Solos. |
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| 12. | | PEREZ, D. V.; ALCANTARA, S. de; RONA, G. B.; BETTIOL, W.; MORICONI, W. Efeito residual da aplicação de biossólido. In: REUNIÃO BRASILEIRA DE FERTILIDADE DO SOLO E NUTRIÇÃO DE PLANTAS, 28.; REUNIÃO BRASILEIRA SOBRE MICORRIZAS, 12.; SIMPÓSIO BRASILEIRO DE MICROBIOLOGIA DO SOLO, 10.; REUNIÃO BRASILEIRA DE BIOLOGIA DO SOLO, 7., 2008, Londrina. FertBio 2008: desafios para o uso do solo com eficiência e qualidade ambiental: anais. Londrina: Embrapa Soja: SBCS: IAPAR, UEL, 2008. 4p. CD-ROM.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 13. | | PEREZ, D. V.; ALCANTARA, S. de; RONA, G. B.; BETTIOL, W.; MORICONI, W. Efeito residual da aplicação de biossólido. In: REUNIÃO BRASILEIRA DE FERTILIDADE DO SOLO E NUTRIÇÃO DE PLANTAS, 28.; REUNIÃO BRASILEIRA SOBRE MICORRIZAS, 12.; SIMPÓSIO BRASILEIRO DE MICROBIOLOGIA DO SOLO, 10.; REUNIÃO BRASILEIRA DE BIOLOGIA DO SOLO, 7., 2008, Londrina. FertBio 2008: desafios para o uso do solo com eficiência e qualidade ambiental: resumos. Londrina: Embrapa Soja: SBCS: IAPAR, UEL, 2008. 1 CD-ROM.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 14. | | SANTOS, F. A. dos; RONA, F. B.; SERRENHO, F. G.; ALCANTARA, S. M.; PEREZ, D. V. Efeito residual da aplicação de lodo de esgoto nas propriedades químicas de um Latossolo Vermelho. In: JORNADA GIULIO MASSARANI DE INICIAÇÃO CIENTÍFICA, ARTÍSTICA E CULTURAL DA UFRJ, 30., 2008, Rio de Janeiro. Livro de resumos [...]. Rio de Janeiro: Universidade Federal do Rio de Janeiro, 2008. p. 250. Ref. 707.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Solos. |
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| 15. | | ALCANTARA, S. de; PEREZ, D. V.; MENEGHELI, N.; PEREIRA, E. M.; BOEIRA, R. C. Efecto del uso del lodo generado en el tratamiento de las aguas negras en la acumulación de Fe, Mn, Ni, Zn, Cu e Cr en suelos brasileños. CONGRESO INTERNACIONAL DE QUÍMICA E INGENIERÍA QUÍMICA= INTERNATIONAL CONGRESS ON CHEMISTRY AND CHEMICAL ENGINEERING, 5., 2004, La Habana. Memorias... La Habana: Sociedad Cubana de Química, 2004. 1 CD ROM.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 16. | | ALCANTARA, S. de; PEREZ, D. V.; ALMEIDA, M. R. A. de; SILVA, G. M. da; POLIDORO, J. C.; BETTIOL, W. Chemical changes and heavy metal partitioning in an oxisol cultivated with maize (Zea mays, L.) after 5 years disposal of a domestic and an industrial sewage sludge. Water, Air and Soil Pollution, v. 203, n. 1-4, p. 3-16, Oct. 2009.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Meio Ambiente; Embrapa Solos. |
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| 17. | | VASCONCELOS, T. N. C.; ALCANTARA, S.; ANDRINO, C. O.; FOREST, F.; REGINATO, M.; SIMON, M. F.; PIRANI, J. R. Fast diversification through a mosaic of evolutionary histories characterizes the endemic flora of ancient Neotropical mountains. Proceedings of the Royal Society B, v. 287, n. 1923, 2020.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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| 18. | | SANTOS, F. A. dos; SERRENHO, F. G.; RONA, G. B.; ALCANTARA, S. de; PEREZ, D. V.; BETTIOL, W.; MORICONI, W. Efeito residual da aplicação de biosólido na cultura do milho. In: SIMPÓSIO INTERNACIONAL DE MEIO AMBIENTE, 4., 2009, Rio de Janeiro. Resumos expandidos. Rio de Janeiro: UFRJ, 2009. p. 460-463.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Meio Ambiente; Embrapa Solos. |
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| 19. | | SERRENHO, F. G.; RONA, G. B.; SANTOS, F. A. dos; ALCANTARA, S. M. de; PEREZ, D. V. Impacto da aplicação de lodo de caleiro em um Argissolo Vermelho-Amarelo no Acre. In: JORNADA GIULIO MASSARANI DE INICIAÇÃO CIENTÍFICA, ARTÍSTICA E CULTURAL DA UFRJ, 30., 2008, Rio de Janeiro. Livro de resumos [...]. Rio de Janeiro: Universidade Federal do Rio de Janeiro, 2008. p. 250. Ref. 693.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Solos. |
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| Registros recuperados : 33 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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